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Computational modeling and fMRI show the roles of brain regions in behavioral control

https://www.cell.com/neuron/abstract/S0896-6273(13)01125-2

John O’Doherty of the Caltech Brain Imaging Center has pinpointed areas of the brain—the inferior lateral prefrontal cortex and frontopolar cortex—that seem to serve as the “arbitrator” between model-based and model-free decision-making systems, weighing the reliability of the predictions each makes and then allocating control accordingly.  Professor O’Doherty believes that this can lead to better treatments for brain disorders, such as drug addiction, and psychiatric disorders, such as obsessive-compulsive disorder. These disorders, which involve repetitive behaviors, may be driven in part by malfunctions in the degree to which behavior is controlled by the habitual system versus the goal-directed system.

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