Browsing Category: Brain

Implanted ultrasound allows powerful chemotherapy drugs to cross the blood brain barrier

Adam Sonaband and Northwestern colleages used a skull-implantable ultrasound device to open the blood-brain barrier and repeatedly permeate critical regions of the human brain, to deliver intravenous chemotherapy to glioblastoma patients. This is the first study to successfully quantify the effect of ultrasound-based blood-brain barrier opening on the concentrations of chemotherapy in the human brain. […]

Study: Molecular mechanism of accelerated cognitive decline in women with Alzheimer’s

Hermona Soreq, Yonatan Loewenstein, and Hebrew University of Jerusalem colleagues have uncovered a sex-specific molecular mechanism leading to accelerated cognitive decline in women with Alzheimer’s disease. Current therapeutic protocols are based on structural changes in the brain and aim to delay symptom progression. Women typically experience more severe side effects from these drugs. This research […]

Donanemab slowed memory decline by 35%, disease progression by 39%, in Alzheimer’s trial

Patients who received Eli Lily’s monthly donanemab infusion in an 18-month study demonstrated a 35% slower decline in memory, thinking, and ability to perform activities of daily living, and were 39% less likely to progress to the next stage of the disease. Brain plaque was also reduced significantly. The risk of the drug is brain […]

AI reconstructs viewed images

Yu Takagi, Shinji Nishimoto and Osaka University colleagues have published a  study which demonstrates that AI can read brain scans and re-create largely realistic versions of images a person has seen. Future applications could include enabling communication of people with paralysis, recording dreams, and understanding animal perception, among others. Additional training was used on the existing text-to-image generative […]

qMRI for early detection of Parkinson’s disease

Aviv Mezer and Hebrew University colleagues used quantitative MRI to identify cellular changes in Parkinson’s disease. Their method enabled them to look at microstructures in the striatum, which is known to deteriorate during disease progression. Using a novel algorithm developed by Elior Drori, biological changes in the striatum were revealed, and associated with early stage […]

Non-invasive stimulation improves memory in study

In a recent study, Boston University professor Robert Reinhart used tACS to stimulate brain activity in 150 people aged 65-88, resulting in memory improvements for one month. Stimulating the dorsolateral prefrontal cortex improved long-term memory, while stimulating the inferior parietal lobe, with low-frequency electrical currents, boosted working memory. Participants were asked to recall 20 words […]