All Posts By: lisaweiner

Study: Molecular mechanism of accelerated cognitive decline in women with Alzheimer’s

Hermona Soreq, Yonatan Loewenstein, and Hebrew University of Jerusalem colleagues have uncovered a sex-specific molecular mechanism leading to accelerated cognitive decline in women with Alzheimer’s disease. Current therapeutic protocols are based on structural changes in the brain and aim to delay symptom progression. Women typically experience more severe side effects from these drugs. This research […]

Wearable sensor evaluates human tissue stiffness

Sheng Xu and colleagues have developed a wearable, stretchable device that non-invasively evaluates the stiffness of human tissue, at an improved penetration depth, and for a longer period than, existing methods. An ultrasonic array facilitates serial, non-invasive, three-dimensional imaging of tissues, four centimeters below the surface of human skin, at a spatial resolution of 0.5 […]

Donanemab slowed memory decline by 35%, disease progression by 39%, in Alzheimer’s trial

Patients who received Eli Lily’s monthly donanemab infusion in an 18-month study demonstrated a 35% slower decline in memory, thinking, and ability to perform activities of daily living, and were 39% less likely to progress to the next stage of the disease. Brain plaque was also reduced significantly. The risk of the drug is brain […]

Pain management via implanted, bioresorbable drug delivery device

John Rogers has developed a wireless, self-powered, bioresorbable implant for programmed drug delivery, enabling precision pain management. When exposed to an external light source, the implant’s wavelength-sensitive phototransistor opens a gate, releasing a pre-loaded reservoir of a drug into the body. It dissolves after the regimen is complete, eliminating the need for surgery to remove […]

Proof of concept wrist sensor could detect heart-vessel blockage in 3-5 minutes

UW’s Graham Nichol and Harborview Medical Center colleagues studying the reliability of a troponin-detecting, wrist-worn sensor in arriving cardiac arrest patients. Identifying heart-vessel blockage quickly is crucial to ensuring rapid, appropriate intervention. Traditional EKG diagnosis can lack accuracy, and blood testing for troponin can take hours. The novel “Tropsensor,” being commercialized by rce, is designed […]

Smart bandage based closed loop wound monitoring and treatment system

Caltech professor Wei Gao has developed a smart bandage for chronic wounds, made from a flexible and stretchy polymer containing embedded electronics and medication. The electronics allow the sensor to monitor uric acid, lactate, pH level and wound temperature, indicating inflammation or bacterial infection. Data from the wound is transmitted wirelessly to the patient or […]

In ear PPG used to measure blood glucose levels in proof of concept study

Danilo Mandic and Imperial College colleagues have developed a novel in-ear PPG device for continuous blood glucose level measurement, using the infrared wavelength of a pulse oximeter. In a recent proof of concept study, non-diabetic, pre-diabetic, type I diabetic, and type II diabetic states were considered. Recordings spanned 9 days, in both fasting and post carbohydrate consumption […]

AI reconstructs viewed images

Yu Takagi, Shinji Nishimoto and Osaka University colleagues have published a  study which demonstrates that AI can read brain scans and re-create largely realistic versions of images a person has seen. Future applications could include enabling communication of people with paralysis, recording dreams, and understanding animal perception, among others. Additional training was used on the existing text-to-image generative […]