Categories
Eyes Wearables

Wearable analyzes faces, voices, surroundings

Professor Amnon Shashua is the founder of  Mobileye, a revolutionary computer vision approach to driverless cars.  He is also the developer of OrCam, artificial vision technology to assist the visually impaired.  This week he announced Casie, a wearable personal assistant.

The device is meant for the masses, but could also help the disabled. It looks like a USB stick, and can be clipped onto clothing or a necklace.  A camera and microphone record  images and sounds from one’s surroundings. Algorithms analyze faces, voices, and surrounding sights and sounds.  The information is sent to a phone, where an app can match it with social media and other data.  To ensure privacy, video and audio content are deleted after  interaction data is collected and analyzed.

Categories
Eyes fitness Wearables

Optical frame integrated health tracker

VSP Global‘s Project Genesis integrates health tracking technology into optical frames.  Steps, calories burned, activity time and distance traveled are calculated by sensors at the part of the frame that touches one’s temple.

Building wearable technology into stylish glasses, worn every day to improve vision, increases the potential for mass adoption.

The prototype is now being tested on 26 of the company’s own employees.

WEARABLE TECH + DIGITAL HEALTH NYC 2015 – JUNE 30 @ NEW YORK ACADEMY OF SCIENCES.  REGISTER HERE.

Categories
Brain Eyes

Wireless brain chip restores vision, bypasses eye

Monash University’s Bionic Eye will be trialed in humans next year. The study is being led by Professor Jeffrey V. Rosenfeld.

Patients who have lost their sight will have tiny “ceramic tiles” implanted into their brain’s visual cortex. The device bypasses the normal visual pathway, unlike the other bionic eyes in development, which rely on an implant in the retina.

A glasses mounted digital camera  captures images before transferring them to a small vision processing device. Once processed, the image is transferred to an antenna attached to the back of a glasses frame. It is then wirelessly transmitted to the brain, where it is received by the small ceramic tiles implanted during surgery. The tiny tiles, each containing 43 microelectrodes​, measure 9mm by 9mm.

WEARABLE TECH + DIGITAL HEALTH NYC 2015 – JUNE 30 @ NEW YORK ACADEMY OF SCIENCES.  EARLY REGISTRATION RATE ENDS FRIDAY, 5/15.

Categories
Brain Eyes

Gold nanoparticles enable optogenetics with out genetic manipulation

University of Chicago‘s Francisco Bezanilla has published a study detailing the use of targeted gold nanoparticles to allow light to activate neurons.  He describes it as optogenetics with out genetic manipulation.

Optogenetics has  relied on genetic modification, limiting its use to few model organisms. Bezanilla previously demonstrated that normal, non-genetically modified neurons can be activated by heat generated by IR pulses. This method lacks specificity and can damage cells. To improve the technique, he used 20-nm gold particles that, when stimulated with green light, absorb and convert light energy into heat.

Two kinds of nanoparticles were tested : ones coupled with a synthetic molecule based on Ts1,  and ones coupled with antibodies that bind to ion channels.  Nanoparticle treated neurons were readily activated by photothermal stimulation. Untreated neurons were unresponsive.  Targeted neurons could be stimulated repeatedly with out cell damage. Some individual neurons produced more than 3,000 action potentials over 30 minutes with no reduction in efficacy.

Nanoparticles were  also tested on complex brain tissue using thin slices of mouse hippocampus.  Groups of neurons  were activated and their activity patterns observed. Treated neurons could still be stimulated after being continuously washed for 30 minutes, indicating that the nanoparticles were tightly bound to the cell surface. Excess nanoparticles wash away, minimizing potentially harmful elevated temperatures.

The ability of nanoparticles to be coupled to different antibodies and retain efficacy suggests flexibility for future applications, including human therapeutic development.

This could, one day, improve the treatment of retinal diseases, such as age-related macular degeneration, where photoreceptor cells that absorb light signals are damaged or dead. The retinal nerve cells that carry visual information to the brain often remain intact and healthy. Nanoparticles targeted to these cells could potentially absorb light and directly stimulate the neurons, bypassing defective photoreceptors.

Although no harmful effects were observed, the researchers said that toxicity is possible, and are now testing the technique in animal models to further evaluate its therapeutic potential.

Wearable Tech + Digital Health NYC 2015 – June 30 @ New York Academy of Sciences.  Early registration rate ends today, March 27th.

Categories
Brain Eyes

Video game trains brain to combat amblyopia

Game developer Ubisoft, with Amblyotech and McGill University,  has released “Dig Rush,” a video game used to treat amblyopia.

Amblyopia is caused when the eyes and the brain aren’t working together, because one eye is stronger or the eyes are misaligned. Patching, the traditional treatment for amblyopia, attempts to force the weaker eye to work harder by covering the stronger eye.  This often fails because social stigmas and long treatment times lead to poor compliance and a high relapse rate.

The glasses and content of Dig Rush use both eyes binocularly to train the brain, to improve visual acuity, instead of training only the weak eye.

After 11 clinical trials of 200 adults and children, recommended treatment is one daily hour of game play for 4-6 weeks.

Wearable Tech + Digital Health NYC 2015 – June 30 @ New York Academy of Sciences

Categories
Eyes

Telescopic lens zooms with a wink

EPFL‘s Eric Tremblay and DARPA have developed contact lenses with integrated tiny telescopic lenses to boost vision. The lens is controlled by smart glasses that respond to the winking of an eye, and provides magnification of up to 2.8 times.

This can be a visual aid for Age-related Macular Degeneration and other conditions, in addition to the originally intended military use.

The prototype is .06 in. thick and contains a very thin, reflective, two-part magnifying region that is turned on and off by defined eyelid movements.  It can differentiate between longer, deliberate winks and normal blinks.  The accompanying glasses  allow the wearer to wink with the right eye to zoom in, and wink with the left eye to return to standard vision.

The telescoping lenses are created with larger, rigid scleral lenses, placed on the the white of the eye.  They are made from precision-machined plastic components, tiny aluminum mirrors, and thin polarizing films,  held together with biologically safe adhesives. The necessary constant stream of oxygen is provided by tiny air channels across the structure of the lens.

Wearable Tech + Digital Health NYC 2015 – June 30 @ New York Academy of Sciences

Categories
Eyes

Sensor glasses support retinal prosthesis

The Johns Hopkins Applied Physics Lab and Second Sight are developing  glasses with embedded vision and eye tracking sensors to be used with a  new retinal prosthesis system.  The system will identify obstacles, doorways, hallways, and household objects and their relative positions. The information will be projected into the retinal prosthesis, bypassing the damaged rods and cones in the retina.

The components are meant to enable APL‘s  broader vision of a semiautonomous controller for assistive robotic manipulators and remote devices, called Hybrid Augmented Reality Multimodal Operation Neural Integration Environment (HARMONIE).

Wearable Tech + Digital Health NYC 2015 – June 30 @ New York Academy of Sciences

Categories
Eyes

Bionic eye prototype stimulates visual cortex to restore sight

The Monash Vision Group is building a bionic eye in an attempt to restore sight by transmitting wireless signals directly to an implant in the brain, bypassing the eye.

The MVG system bypasses the retina and optic nerve and wirelessly stimulates the ‘vision’ center of the brain using implantable electrode arrays.  A digital camera is embedded in headwear that captures images from the user’s environment.  Digital processors and computer algorithms modify the images.  A wireless transmitter presents the images to microchips in an implant surgically inserted at the back of the brain.  The chips stimulate the visual cortex with electrical signals using arrays of micro-sized electrodes, producing small flashes of light (phosphenes) in a 2-dimensional array.  A wearer can be trained to use the phosphenes to navigate and recognize objects.  MVG is able to implant 473 electrodes with its first prototype, depending on the size and location of a patient’s visual cortex.

Bionic Vision Australia is also developing a solution to restore site  — a microchip inserted into a patient’s retina.  The system consists of a camera attached to glasses which transmit high-frequency radio signals to an implanted microchip.  Electrodes on the implanted chip convert the signals to electrical impulses to stimulate cells in the retina that connect to the optic nerve.  The impulses are passed down along the optic nerve to the vision processing centers of the brain, where they are interpreted as images.  The company is working on three devices: an early prototype with 24 electrodes, a wide-view device with 98 electrodes, and a high-acuity device with 1024 electrodes.

Categories
Eyes Nanotubes

Carbon nanotube artificial retina restores light sensitivity

Tel Aviv University, The Hebrew University of Jerusalem and Newcastle University researchers are developing an artificial retina that sends sensory signals to the brain to address vision loss.  Several groups are attempting this, but have had issues with metallic parts, cumbersome wiring, or a low resolution outcome.

The TAU, HUJI and Newcastle team is working on a more efficient, higher resolution device. Semiconductor nanorods and carbon nanotubes were combined to create a wireless, light-sensitive, flexible film that could potentially act in the place of a damaged retina. When tested with a chick retina that normally doesn’t respond to light, the film absorbed light and sparked neuronal activity.

Categories
Eyes Wearables

Bluetooth headset guides the visually impaired

Microsoft is collaborating with Guide Dogs for the Blind and AfterShokz on Cities Unlocked, a prototype headset, smartphone and navigation system for the visually impaired.

The technology helps a user find his/her way, describes potential hazards, such as low-hanging trees, and highlights attractions, including restaurants, on the route.

The headset uses bone-conducting audio that does not cover the ears, ensuring that the wearer hears traffic noises and can have a conversation. It rests in front of the ear and it uses Bluetooth signals to transmit cues into a series of clicks, beeps, and voice notifications.

Categories
Brain Eyes Wearables

More realistic virtual reality — Google hopes

Little is known about MagicLeap, recently backed by Google, representing an assumed commitment to the gaming space, with potential BCI applications.  Patent applications suggest that the company provides display technology that can trick the human visual system better than existing virtual reality displays.

Reports discuss an improved virtual reality user interface that lets one’s eyes focus on depth as in the real world, rather than remaining focused on the screen in front of them. The company claims to be able to create the same kind of 3-D patterns of light rays, known as “light fields,” that eyes take in from real objects. Other descriptions mention infrared sensors and eye-tracking cameras to help the device react to the external environment.

Categories
Eyes Sensors Wearables

Google/Novartis “smart lens” monitors diabetic eyes, helps presbyopia

Google announced its “smart lens” prototype 6 months ago.  (See ApplySci,  January 14 2014).  Today they have partnered with Novartis to accelerate its development as a tool to manage eye conditions.

Non-invasive sensors and microchips embedded in the lens monitor fluid to provide continuous, minimally invasive glucose measurement. The data is sent wirelessly to a mobile device.

The technology can help  restore the eye’s natural autofocus on near objects in presbyopia as an accommodative contact lens.  It can also be implanted as an intraocular lens during refractive cataract surgery.

Monitoring glucose levels through the lenses could  be easier and more comprehensive than current techniques, which require diabetics to draw blood from their fingers.