Browsing Tag: Featured

Directional DBS system targets GPi to relieve Parkinson’s symptoms

Abbott received FDA approval for an expanded indication for its Deep Brain Stimulation system, to include targeting of internal globus pallidus. The GPi plays an integral role in motor function. When targeted with DBS, Parkonson’s symptoms not adequately controlled by medication can improve. The directed stimulation system is now approved for all major targets used […]

Genetic “Ageotypes” predict health as we age

Stanford’s Michael Snyder has categorized how humans age into different classes called “ageotypes”: metabolic, immune, hepatic and nephrotic. 43 healthy men and women between the ages of 34 and 68 were profiled, with extensive measurements of certain microbes and biological molecules, such as proteins, metabolites and lipids, taken at least five times over two years. […]

George Church on reversing aging | ApplySci @ Harvard

George Church again keynoted the ApplySci Boston conference, this year at Harvard Medical School on November 14, 2019. Click to view his groundbreaking talk on reversing aging. Join ApplySci at the 13th Wearable Tech + Digital Health + Neurotech Silicon Valley conference on February 11-12, 2020 at Quadrus Sand Hill Road.  Speakers include:  Zhenan Bao, Stanford – Vinod […]

Joe Wang on next-generation biosensors

Joseph Wang is the SAIC Endowed Chair professor, Chairman of the NanoEngineering Department and Director of the Center for Wearable Sensors at University of California, San Diego, and Editor-in-chief of the journal Electroanalysis. A prolific researcher with more than 1,200 papers and 100,000 citations, he recently developed an ultrasound patch to monitor blood pressure; self-propelled and targeted drug delivery; and continuous […]

AI for (much) earlier breast cancer detection – Constance Lehman

Connie Lehman — Professor, Radiology, Harvard Medical School; Chief of Breast Imaging, radiology, Massachusetts General Hospital; Co-director of AVON Breast Center, Radiology, Massachusetts General Hospital; and Director, Breast Imaging Research Center, Radiology, Massachusetts General Hospital spoke at ApplySci’s recent conference at Harvard Medical School. Click to listen to her talk on using AI to discover breast cancer 5 years […]

Invasive deep brain stimulation for alcoholism?

Stanford’s Casey Halpern and Allen Ho have used deep brain stimulation to target nucleus accumbens, thought to reduce impulsive behavior, to combat alcoholism in animal and pilot human studies. DBS is used in severe Parkinson’s disease and is not approved by the FDA for addiction. Infection and other complications are risks of this invasive surgery. ApplySci hopes that […]

AI – optimized glioblastoma chemotherapy

Pratik Shah, Gregory Yauney,  and MIT Media Lab researchers have developed an AI  model that could make glioblastoma chemotherapy regimens less toxic but still effective. It analyzes current regimens and iteratively adjusts doses to optimize treatment with the lowest possible potency and frequency toreduce tumor sizes. In simulated trials of 50 patients, the machine-learning model […]