Browsing Category: Cancer

AI for (much) earlier breast cancer detection – Constance Lehman

Connie Lehman — Professor, Radiology, Harvard Medical School; Chief of Breast Imaging, radiology, Massachusetts General Hospital; Co-director of AVON Breast Center, Radiology, Massachusetts General Hospital; and Director, Breast Imaging Research Center, Radiology, Massachusetts General Hospital spoke at ApplySci’s recent conference at Harvard Medical School. Click to listen to her talk on using AI to discover breast cancer 5 years […]

PET scan tracer detects both cancer and lung disease

Stanford’s Sanjiv Gambhir has developed an imaging molecule that can identify pancreatic, cervical and lung cancer early– and, surprisigly, hard-to-detect idiopathic pulmonary fibrosis.  The tracer clings to integrin alpha-v beta-6. In a PET scan, the tracer glows due to radioactivity emissions, which allows doctors to see exactly where the tracer is docked in the body. A […]

Infrared light detects tumors under the skin

Stanford’s Hongjie Dai has developed a deep-tissue imaging technique that clearly illuminates tumors beneath the skin.  It relies on nanoparticles containing erbium,  which glows in the infrared.  The promising technology has only been tested on mice, so far. In a study, the technique was used to predict cancer patient response to immunotherapy, and to measure drug […]

AIgorithm detects cancer potential of pancreatic cysts

CompCyst is a proof-of-concept study, led by Anne Marie Lennon at Johns Hopkins, which uses AI to more accurately determine which pancreatic cysts will become cancerous. The test evaluates molecular and clinical markers in cyst fluids, and could significantly improve detection rates vs. current clinical and imaging tests. In the study, the researchers evaluated molecular profiles, […]

“Monorail” could halt spread of brain tumors

Duke’s Ravi Bellamkonda has developed a “Tumor Monorail” which tricks aggressive brain tumors such as glioblastoma into migrating into an external container rather than throughout the brain.  It has been designated “Breakthrough Device” by the U.S. Food and Drug Administration (FDA). The device mimics the physical properties of the brain’s white matter to entice aggressive tumors to […]

AI – optimized glioblastoma chemotherapy

Pratik Shah, Gregory Yauney,  and MIT Media Lab researchers have developed an AI  model that could make glioblastoma chemotherapy regimens less toxic but still effective. It analyzes current regimens and iteratively adjusts doses to optimize treatment with the lowest possible potency and frequency toreduce tumor sizes. In simulated trials of 50 patients, the machine-learning model […]

Hydrogen peroxide sensor to determine effective chemotherapy

MIT’s Hadley Sikes has developed a sensor that determines whether cancer cells respond to a particular type of chemotherapy by detecting hydrogen peroxide inside human cells. The technology could help identify new cancer drugs that boost levels of hydrogen peroxide, which induces programmed cell death. The sensors could also be adapted to screen individual patients’ […]