Browsing Category: Cancer

Urine test for cancer biomarkers

Minoru Sakairi and Hitachi scientists have developed a urine test for early cancer detection. 5,000 types of metabolites can be analyzed for cancer biomarkers in urine.  The team began a study three years ago, resulting in the identification of 30 metabolites that can be used to discriminate between healthy people and cancer patients.  Further validation studies […]

AI detects bowel cancer in less than 1 second in small study

Yuichi Mori and Showa University colleagues haved used AI to identify bowel cancer by analyzing colonoscopy derived polyps in less than a second. The  system compares a magnified view of a colorectal polyp with 30,000 endocytoscopic images. The researchers claimed  86% accuracy, based on a study of 300 polyps. While further testing the technology, Mori said that […]

Machine learning improves breast cancer detection

MIT’s Regina Barzilay has used AI to improve breast cancer detection and diagnosis. Machine learning tools predict if a high-risk lesion identified on needle biopsy after a mammogram will upgrade to cancer at surgery, potentially eliminating unnecessary procedures. In current practice, when a mammogram detects a suspicious lesion, a needle biopsy is performed to determine if […]

CRISPR platform targets RNA and DNA to detect cancer, Zika

Broad and Wyss scientists have used an RNA-targeting CRISPR enzyme to detect  the presence of as little as a single target molecule. SHERLOCK (Specific High Sensitivity Enzymatic Reporter UnLOCKing) could one day be used to respond to viral and bacterial outbreaks, monitor antibiotic resistance, and detect cancer. Demonstrated applications included: Detecting the presence of Zika virus in […]

Nanorobots optimize cancer drug delivery, preserve surrounding tissues

Sylvain Martel and Polytechnique Montréal and McGill University colleagues have developed nanorobotic agents that can specifically target active cancerous cells of tumors.  Optimal targeting  could help preserve surrounding organs and healthy tissues, and allow reduced dosage. The nanorobotic agents can autonomously detect oxygen-depleted tumour areas, and deliver the drug to them. These “hypoxic” zones are […]

AI identifies cancer after doctor misdiagnosis, used to personalize care

IBM Watson detected a rare form of leukemia in a patient in Japan, after comparing genetic changes with a database of 20 million research papers. She had been misdiagnosed by doctors for months, and received the wrong treatment for her cancer type. Watson has created partnerships with 16 US health systems and imaging firms to identify cancer, diabetes and […]

Preparation free, ingestible colorectal screening device

Check-Cap is developing a swallowable imaging capsule that screens for colorectal cancer with out requiring  bowel-cleansing preparation. The ingestible capsule transmits X-rays to the intestinal wall and back, creating 3D images of the colon’s internal surface and enabling detection of clinically significant polyps.  Given Imaging,  also based in Israel, used light based (vs. X ray) […]

Non-invasive electric field treatment for glioblastoma

Optune by Novocure  uses targeted electric fields to disrupt cancer cell division and cause cancer cell death.  500 hospitals globally can prescribe the FDA approved treatment to glioblastoma patients. “Tumor Treating Fields” are low intensity, alternating electric fields within the intermediate frequency range. TTFields disrupt cell division through physical interactions with key molecules during mitosis. […]