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Artificial spleen-on-a-chip to treat sepsis

http://wyss.harvard.edu/viewpressrelease/108/

Harvard researchers are developing a device that could be used to rapidly remove pathogens from the blood of patients with sepsis.  The dialysis-like machine acts as an artificial spleen, filtering the blood using injectable magnetic nanobeads engineered to stick to microorganisms and toxins.  After the beads are injected, blood is removed and run through a device that uses a magnetic-field gradient to extract the nanobead-bound germs. The blood is then returned to the body.  The team at the Wyss Institute for Biologically Inspired Engineering hopes that the device will be able to identify the specific microorganism causing the patient’s blood infection.  This could help physicians more quickly determine the most effective antibiotic treatment.

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Conference Monitoring Sensors

Bio-integrated electronic tattoo measures vital signs and muscle movement

http://www.utexas.edu/know/2013/06/07/high-tech-tattoos-health-care-solutions/

Professor Nanshu Lu at The University of Texas is developing the next-generation of flexible/stretchable electronics, photonics and therapeutics.  Pioneered by John Rogers at the University of Illionois, flexible skin “tattoos” measure vital signs and muscle movement, transmitting data wirelessly and harvesting solar energy. Future versions may play critical roles inside the body in watching for signs of disease or damage, or treating problems automatically.

Professor Lu has designed a bio-integrated electronic tattoo. The ultrathin, ultrasoft stamp-sized patch clings to the human skin without adhesive, which would interrupt electrical connectivity.  Lu’s area of expertise — the interface of flexible electronics with biosystems — is one of three areas crucial to the future of bio-integrated electronics, the others being wireless data transmission and wireless power transmission.

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Wireless, dissolvable circuits could kill bacteria

http://www.bbc.com/future/story/20130524-zapping-bacteria-the-wireless-way

Professor John Rogers of the University of Illinois has created bio-absorbable electronic circuits which could be implanted into wounds and powered wirelessly to destroy bacteria during healing before dissolving harmlessly into body fluids once their job is done.  Rogers and others have previously reported biodegradable flexible circuits and electronic devices that can be safely laid directly onto skin. But their success in making their circuits wireless could prove crucial to many potential applications, especially in medicine.

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Neural codes of diseases studied to discover potential “electroceutical” treatments

http://www.reuters.com/article/2013/04/10/us-glaxosmithkline-electroceuticals-idUSBRE9390VM20130410

The Feinstein Institute for Medical Research, the University of Pennsylvania, MIT and GlaxoSmithKline are collaborating on research which aims to discover medicines that use electrical impulses to regulate the body’s organs and functions.

Nearly all organs and functions in the body are regulated through circuits of neurons that communicate through electrical impulses. There already exist devices that use electrical impulses to treat disease (i.e., pacemakers, defibrillators, deep-brain stimulation), but these devices do not target specific cells in the body. Researchers now believe it is possible to create devices that control action potentials in individual neurons, a critical step in developing technologies to use neural circuits to control specific cells. It may be possible to intervene in a broad spectrum of diseases, like inflammatory and autoimmune diseases, because these conditions can be controlled by neurons.

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3-D printer builds synthetic tissues

http://phys.org/news/2013-04-d-printer-synthetic-tissues.html

Oxford University scientists have created a custom-built programmable 3D printer that can create materials with several of the properties of living tissues.

The new type of material consists of thousands of connected water droplets, encapsulated within lipid films, which can perform some of the functions of the cells inside our bodies. These printed ‘droplet networks’ could be the building blocks of a new kind of technology for delivering drugs to places where they are needed and potentially one day replacing or interfacing with damaged human tissues. Because droplet networks are entirely synthetic, have no genome and do not replicate, they avoid some of the problems associated with other approaches to creating artificial tissues – such as those that use stem cells.

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IBM 5 focuses on human senses

http://www.ibm.com/smarterplanet/us/en/ibm_predictions_for_future/ideas/index.html

IBM published its annual report, this year focusing on the five basic senses.  Highlighted future abilities of computers include:

-the ability to identify distinctive image features, foregoing the need for tags

-the development a sense of taste

-smelling computers that detect explosives in the public and cancer in our bodies

-touch sensitivity, allowing us to feel textures

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Conference

4 top trends in digital healthcare

http://blogs.computerworld.com/healthcare-it/21405/top-four-trends-will-shape-digital-health

As we approach 2013, the following trends continue to spawn companies, investment, and technologies:

  1. The proliferation of personalized mobile health technologies. 
  2. The maturation of the Big Data ecosystem in health care.
  3. The rise of health startup accelerators.
  4. The emergence of health care exchange and alternative care delivery platforms.