DEEP TECH HEALTH + NEUROTECH
Early Parkinson’s Disease patients benefit significantly from levodopa, to replace dopamine to restore normal motor function. As PD progresses, the brain loses more dopamine-producing cells, which causes motor complications and unpredictable responses to levodopa. Doses must be increased over time, and given at shorter intervals. Regimens are different for each person and may vary from […]
Ruhr University professor Sebastian Kruss, with Max Planck researchers Sofia Elizarova and James Daniel, has developed a sensor that can visualize the release of dopamine from nerve cells with unprecedented resolution. The team used modified carbon nanotubes that glow brighter in the presence of the messenger substance dopamine. Eizarova said that the sensor “provides new […]
The “Lipid Invasion Model” argues that lipids entering the brain due to blood brain barrier damage is the determining cause of the Alzheimer’s Disease. The presence of excess lipids in the brain cells of Alzheimer’s patients is an element of Alois Alzheimer’s 1906 research, but little has been published about this connection since. The hypothesis, […]
A small Boston Children’s Hospital study led by Assistant Professor Emi Takahashi and postdoc Alpen Ortug showed increased volume of the insular lobe as a potential strong prenatal MRI biomarker that could predict the emergence of ASD later in life. It revealed significant differences in brain structures at 25 weeks’ gestation between children who were […]
Nolan Williams, Alan Schatzberg, and Stanford colleagues have published a small, double blind study showing that high dose, noninvasive, magnetic brain stimulation alleviated depression symptoms in 80% of participants. Stanford accelerated intelligent neuromodulation therapy (SAINT) is an intensive, individualized form of transcranial magnetic stimulation. Effects were seen within days and lasted months. Side effects included […]
George Sothart and University of Bath colleagues have developed a new, EEG + game memory assessment technique which could enable the earlier diagnosis of Alzheimer’s disease, the underlying cause of around 60% of dementia cases.. The need for early diagnosis tools to help doctors to prescribe lifestyle interventions to slow the rate of cognitive decline […]
The Apple/UCLA project “Seabreeze” and Apple/Biogen project “Pi” represent a further move into iPhone health monitoring. According to the Wall Street Journal, Apple is attempting to develop an algorithm to identify depression and cognitive decline from sleep patterns, mobility, and how one uses the phone — for example, how often they look at its clock. […]
The US Army and USC Prof Maryam Shanechi have developed an algorithm that can determine which specific behaviors—like walking and breathing—belong to specific brain signals. Segmenting brain signals has been notoriously difficult, as all signals associated with tasks mix together. Shanechi and her team used the algorithm to separate behaviorally relevant brain signals from behaviorally […]
David Martin and University of Delaware colleagues have developed a bio-synthetic coating for electronic components that could avoid the scarring (and signal disruption) caused by traditional microelectric materials. The PEDOT polymer improved the performance of medical implants by reducing their opposition to an electric current. Pedot film was used with an antibody to stimulate blood […]
Penn State’s Aida Ebrahimi and Maurico Terrones, RPI’s Humberto Terrones, and colleagues, have developed a highly sensitive, non-invasive wearable Dopamine sensor platform. The goal is the use of the technology to develop wearable sensors able to track and eventually treat conditions caused by too much (ie schizophrenia) or too little (ie Parkinson’s, depression) dopamine. The […]