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Brain scan for Alzheimer’s diagnosis

http://www.imperial.nhs.uk/aboutus/news/news_042335

Tomorrow, London’s Imperial College will be the first to perform a brain scan which could lead to more accurate diagnosis of Alzheimer’s disease and other dementias.

The test involves giving the patient a small amount of a radiopharmaceutical which binds to amyloid plaques, showing them in a brain scan. Amyloid plaques in the brain are one of the hallmarks of Alzheimer’s disease, so a negative scan effectively excludes a diagnosis of the condition.

This is the first time that clinicians have been able to see these plaques while a patient is alive, marking a significant breakthrough in the diagnosis of dementia. The presence of plaques in the new scan will also help to ensure that patients with memory problems who take part in clinical trials for amyloid-targeting drugs are appropriately selected.

Until now, Alzheimer’s disease could only be diagnosed definitively via brain autopsy.

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