Eliminating sugar slows cancer growth

http://www.scotsman.com/news/health/cutting-off-sugar-could-stop-cancer-growth-1-3024411

Old but important news: Eliminating sugar can slow cancer growth.

Researchers were aware that all cancer cells are attracted to sugar, grabbing it from the blood before using it to fuel their growth.  In breast cancer the process involves binding proteins called CtBPs together to form pairs known as dimers. These in turn help the cells to multiply and proliferate.  Dr Jeremy Blaydes of the University of Southampton found that chemicals called cyclic peptide inhibitors can block CtBPs and prevent the dimers forming.  The most successful of CtBP blocker, known as CP61, is now being developed as a potential new breast cancer drug.

This concept was put forth in the lecture given by Otto Warburg at his Nobel ceremony in 1931.  The short story: cancerous cells rely more on sugar for their energy consumption than normal cells.

In related news, a new technique for detecting cancer by imaging the consumption of sugar with MRI  has been unveiled by University College London scientists.


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