Tag: Alzheimer's
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Study: Molecular mechanism of accelerated cognitive decline in women with Alzheimer’s
Hermona Soreq, Yonatan Loewenstein, and Hebrew University of Jerusalem colleagues have uncovered a sex-specific molecular mechanism leading to accelerated cognitive decline in women with Alzheimer’s disease. Current therapeutic protocols are based on structural changes in the brain and aim to delay symptom progression. Women typically experience more severe side effects from these drugs. This research…
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Donanemab slowed memory decline by 35%, disease progression by 39%, in Alzheimer’s trial
Patients who received Eli Lily’s monthly donanemab infusion in an 18-month study demonstrated a 35% slower decline in memory, thinking, and ability to perform activities of daily living, and were 39% less likely to progress to the next stage of the disease. Brain plaque was also reduced significantly. The risk of the drug is brain…
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Amyloid beta oligomer blood test could predict Alzheimer’s disease several years in advance
University of Washington’s Valerie Daggett, Dylan Shea, and colleagues, have developed a lab test that can measure levels of amyloid beta oligomers in blood samples. Known as SOBA, the test detected, in a study of 310 subjects, oligomers in the blood of Alzheimer’s patients, but not in most of the control group, which had no…
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Univ. of Reading study links Alzheimer’s disease to blood brain barrier damage
The “Lipid Invasion Model” argues that lipids entering the brain due to blood brain barrier damage is the determining cause of the Alzheimer’s Disease. The presence of excess lipids in the brain cells of Alzheimer’s patients is an element of Alois Alzheimer’s 1906 research, but little has been published about this connection since. The hypothesis,…