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Assistive Technologies BCI Brain

Continuously correcting BCI technique improves precision

Stanford‘s Krishna Shenoy has developed a more precise brain-controlled cursor for a virtual keyboard using a technique that continuously corrects brain readings.

An algorithm analyzes the measured electrical signals that a prosthetic device obtained from sampled neurons. It adjusts  the signals so that the sample’s dynamics were more like baseline brain dynamics.

The thought-controlled keypad would allow a person with paralysis or ALS to run an electronic wheelchair and use a computer or tablet. Today an eye-tracking system is used to direct cursors, or a “head mouse, ” which tracks the movement of the head.  Both are fatiguing, and  neither provides the natural and intuitive control of readings taken directly from the brain.

Stanford University video detailing single trial dynamics of motor cortex and their applications to brain-machine-interfaces:

This video includes two clips. In the first, flashing targets on a virtual keypad are hit by monkeys (not shown) using their hands. The second clip also shows targets being hit. But this time, the motion is directed by an experimental device that taps into the monkey’s brain. This device discerns their intention to hit the target and translates this thought into an electronic command that controls a virtual cursor. In the first clip the monkeys hit 10 targets in 9.9 second with their hands. It takes 11.4 seconds to hit 10 targets using the thought-control device.

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Cancer Sensors

Biochemical sensor helps refine cancer treatment

MIT professor Michael Cima is developing a tiny biochemical sensor that can be implanted in cancerous tissue during a biopsy.  It wirelessly sends  biomarker data to an external device,  allowing doctors to monitor progress, and adjust dosages or switch therapies accordingly.

The sensor fits into the tip of a biopsy needle. It contains 10 microliters of chemical contrast agents typically used for MRI, and an on-board circuit to communicate with the external reader. Real-time, on-demand data concerning two biomarkers linked to a tumor’s response to treatment, pH and dissolved oxygen, is provided.

The goal is to make treatments more targeted and precise, to improve their efficacy and reduce side effects.

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Apps Ears

Video messaging app for the hearing impaired

Glide combines the concepts of WhatsApp with Skype, enabling users to send short videos of themselves. It has become a popular communication tool for the hearing impaired, who use it for sign language messaging.

The app has 20 million registered users.  The company hopes to soon offer instant subtitles for sign language, and the ability to convert text into visual graphics.

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Orthopedics

Gesture controlled driver’s seat improves ergonomics

The Fraunhofer driver’s seat is adjusted with hand gestures to optimize ergonomics and prevent spinal strain.

Pressure responding piezoensors are integrated into the side of the seat to activate the motion controlled system. Seat positions can be stored. Proximity sensors detect changes in electrical fields, as triggered by hand motions. Software interprets the data and determines the hand’s direction of motion, moving the seat accordingly.  An algorithm enables multiple electrodes to be evaluated simultaneously.

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Assistive Technologies

Paralyzed patients move legs with non-surgical stimulation

UCLA and Pavlov Institute‘s transcutaneous stimulation technique helped paralyzed patients regain voluntary movement without surgery.

In a recent study, 5 men, who had been paralyzed for 2-6 years, moved their own legs (with out stimulation) after several weeks of electrical stimulation, physical therapy, and an experimental drug.

Transcutaneous stimulation delivers electrical current to the spinal cord, via electrodes placed on the lower back. This is the first time the stimulation was delivered non-invasively. Previously, an electrical stimulation device had to be surgically implanted on the spinal cord.

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Conference

Jack Young interview at Wearable Tech + Digital Health NYC 2015

Startup Health‘s Unity Stoakes did a series of interviews at ApplySci’s recent Wearable Tech + Digital Health NYC 2015 conference.  Here is his discussion with Jack Young, General Partner at dRx Capital and Head of the Qualcomm Life Fund.  Click to hear Jack’s thoughts  about the future of wearables, venture capital strategy in healthcare, and the Fitbit IPO.

Photo by Yuko Torihara at Wearable Tech + Digital Health NYC 2015.

Categories
Sensors Wearables

Sensor pill for 3D colon imaging

Check Cap, developed by Yoav Kimchy,  is a colon imaging sensor pill.  A patient takes small amounts of a contrast agent with meals.  The pill is swallowed, and after reaching the colon, a signal is emitted in every direction, providing 3D imaging. The data is sent to a wireless patch worn by the patient, and his/her doctor receives a rendering of the colon in 10 minutes.

The technology is based on a gallium nitride microchip that can withstand the high voltage needed by the sensors.  As it is miniaturized, its developers believe that it be used to scan narrower body parts, such as  blood vessels.

Check Cap said that a patient’s radiation exposure is equivalent to a chest-X-ray, or 1/300 of a CTC analysis.

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Asthma Sensors

Street View cars map health-impacting pollutants

Google has partnered with Aclima to map urban air quality through Street View cars.

Mobile sensors on the  cars will  measure nitrogen dioxide, nitric oxide, ozone, carbon monoxide, carbon dioxide, and other  pollutants that can affect health.

A  experiment was conductedin Denver.  The cars drove for 750 hours, over 30 days, and gathered 150 million data points. The testing was done during the DISCOVER-AQ study conducted by NASA and the EPA.

The project will be expanded, beginning in San Francisco this fall.

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Computer Vision

Deep neural networks for face recognition in darkness

Karlsruhe Institute of Technology researchers have used the heat from one’s face to enable facial recognition in darkness. Thermal imaging creates an infrared picture, which can then be matched to a photograph taken in the light.

In a recent study, a “deep neural network” accurately identified faces in the dark 80 percent of the time when shown a large number of photos.  However,  the technology is at an early stage, and was only successful 55 percent of the time when presented with a single  image.

Categories
Sleep

Device scores daily sleep quality

Nintendo has filed a patent for a  device that scores one’s sleep quality each day.   A user’s weight, pulse and movement information, as well as room temperature and humidity, are gathered.  A microphone, camera, thermometer and other sensors calculate a sleep score that will be projected onto the ceiling.

The abstract describes sensors that assess emotions, with out much detail. (The application is written in Japanese.) The challenge is to find a way to use this information to actually improve sleep quality.

Categories
Inflammation

“Smart” drug targets site-specific inflammation

Ben-Gurion University‘s Peleg Rider has developed a drug that targets inflammation in a site-specific manner.  This could improve the body’s  ability to fight infection and reduce side effects.

When injected, it is a non-active drug.  A localized site with excessive inflammation will activate it.  Other anti-inflammatory agents inhibit inflammatory processes throughout the body, including sites of necessary normal inflammatory homeostasis.

When a non-specific agent is used, a patient who suffers from local inflammation might  be exposed to infections at distant sites, such as the lungs. This risk is increased in immunosuppressed, older, and chemotherapy patients.

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Babies Sensors

Simple sensor to prevent car-heat related deaths

All too often we hear about a baby, or person who is unable to speak for him/herself, being left in a hot car, and dying.  ApplySci applauds Evenflo for creating a car seat with a very simple notification sensor that could prevent this.

The Embrace DLX seat, with SensorSafe technology, generates a series of tones when a car is turned off, to remind us that a baby is still in the car.  The company has not described technology for disabled adults, but this is the obvious next step.

The tones are activated through a chest clip and wireless receiver. The receiver also sends alerts if the chest clip becomes unbuckled during transit.